Pepto-Care Oral Suspension 200ml

✔️ Uses of Pepto-Care Oral Suspension

• Diarrhea
• Nausea
• Heartburn
• Indigestion
• Upset stomach

✔️ How does Pepto-Care Oral Suspension work?

• Antimicrobial and anti-inflammatory action: Bismuth subsalicylate exhibits antibacterial properties, reducing the presence of pathogens.
• Antisecretory effect: Salicylate reduces the secretion of fluids in the intestines, which helps relieve diarrhea.

✔️ Side Effects of Pepto-Care Oral Suspension

• Common (≥10%): Nausea (12%)
• Less common (1-10%): Diarrhea (7%), abdominal pain (7%), melena (3%), upper respiratory infection (2%), constipation (2%), anorexia (2%), vomiting (2%), asthenia (2%), discolored tongue (2%), headache (2%), dyspepsia (2%), dizziness (2%)
• Rare (<1%): Stool abnormality (1%), duodenal ulcer (1%), sinusitis (1%), taste alteration (1%), flatulence (1%), GI hemorrhage (1%), pain (1%), insomnia (1%), anal discomfort (1%), paresthesia (1%)
• Frequency not defined: Anxiety, confusion, depression, tinnitus, weakness, gray-black stool, impaction, muscle spasm, neurotoxicity (rare)

✔️ Quick Suggestions:

• Before taking Pepto-Care Oral Suspension, inform your doctor if you have other gastrointestinal disorders.
• Pepto-Care Oral Suspension might cause temporary and harmless darkening of the tongue and/or black stool. Do not panic, inform your doctor.
• Have plenty of fluid while taking Pepto-Care Oral Suspension, particularly with the bedtime dose.
• Let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.

✔️ Indication of Pepto-Care Oral Suspension

Bismuth subsalicylate is an antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.

✔️ Pharmacology

Bismuth subsalicylate is an antacid and anti-diarrheal agent with both antibacterial and gastroprotective properties. It is an insoluble salt composed of salicylic acid and a trivalent bismuth cation, with each molecule containing 58% bismuth and 42% salicylate by weight.

• Pepto-Bismol: Bismuth subsalicylate is the active ingredient in this common over-the-counter medication used to treat temporary discomforts in the stomach and gastrointestinal tract.
• HELIDAC Therapy: A combination treatment (bismuth subsalicylate, metronidazole, and tetracycline) used for the eradication of Helicobacter pylori infections, particularly in patients with H. pylori-related duodenal ulcers.

Its broad applications, ranging from treating common stomach upsets to aiding in treating bacterial infections, highlight its versatility and importance in gastrointestinal health management.

✔️ Dosage & Administration of Pepto-Care Oral Suspension

Adult Dose:

• Adults: 30 mL, 3-4 times daily, 30 minutes before meals.

Child Dose:

• Children (3-12 years): 5-15 mL.
• Children under 3 years: Safety and efficacy not established.

• Drink plenty of clear fluids to prevent dehydration caused by diarrhea.
• Do not use for more than 2 days.

✔️ Interaction

Pepto-Care Oral Suspension contains salicylates therefore care should be exercised if receiving drugs to thin the blood (anticoagulant therapy) or oral medicine for diabetes or treatment for gout or arthritis.

✔️ Contraindications

• Hypersensitivity to bismuth, aspirin, or other salicylates.
• Infectious diarrhea with high fever.
• Von Willebrand disease, hemorrhage, ulcer, or gastrointestinal bleeding with black or bloody stools.
• Hemophilia.
• Pediatric patients with chicken pox or influenza (risk of Reye syndrome).
• Changes in behavior with nausea and vomiting may be an early sign of Reye syndrome.

✔️ Pregnancy & Lactation

• Category C: Potential risk during pregnancy, especially in the early stages.
• Category D in the 3rd trimester: Risk of complications increases significantly.
• Lactation: Salicylates enter breast milk; use with caution while breastfeeding

✔️ Precautions & Warnings

Do not take it with aspirin or other salicylates. Caution should be exercised by patients taking medicines for anticoagulation (thinning of the blood), diabetes, or gout.

✔️ Storage Conditions:

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.